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Celexa (citalopram hydrobromide)

Celexa General Information

Celexa Side Effects

Order celexa online. Celexa is an antidepressant medication used for treating several mood disorders. Celexa belongs to a group of antidepressant drugs called SSRIs.

Celexa Interactions

Celexa Dosages

Celexa Directions

Celexa and Pregnancy

Celexa and Children

Celexa and Seniors

Celexa General Information

Celexa is an antidepressant medication used for treating several mood disorders. Celexa belongs to a group of antidepressant drugs called SSRIs (selective serotonin reuptake inhibitor), which are thought to work by increasing the amount of serotonin (a chemical involved in communication between nerve cells) available to the brain, so that it comes back to typical levels. Low levels of serotonin are thought to be associated with mood disorders, and high levels of serotonin appear to have an antidepressant effect.

Celexa has been shown to be effective in relieving several kinds of emotional disturbance that decrease the ability to function normally, particularly depression. In low doses, Celexa may be used to treat fibromyalgia. Celexa may take several weeks to improve your condition, and works best when taken regularly and at consistent times.

Celexa is currently prescribed as a medication for:

  • Major depressive disorder (Celexa dosage 20-60 mg/day)
  • Depression occurring after stroke (Celexa dosage 20 mg/day)
  • Reduces frequency of tension headaches (Celexa dosage 20 mg/day)
  • May assist recovery from alcohol abuse (Celexa dosage 40 mg/day)
  • Obsessive compulsive disorder (Celexa dosage 20-40 mg/day)
  • Premenstrual dysphoria syndrome (Celexa dosage 20 mg/day)

Celexa, manufactured by Lundbeck, contains 20 mg citalopram as the active ingredient and comes in multiples of 28 tablets.

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Product Price Quantity
Celexa 20 mg, 28 tab $99
Celexa 20 mg, 56 tab $179

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Celexa Side Effects

Celexa side effects are usually temporary and can include the following, based on a dosage of 20-60 mg/day.

Common Celexa Side Effects: Cough, diarrhea, dry mouth, fatigue, insomnia, low blood pressure, nausea, sweating, tremor, weight loss (minor). These side effects typically appear early in treatment, and usually diminish with continued use. If any of them persist, or are bothersome, speak to your doctor. Other Celexa side effects occurred in less than 2% of patients compared with incidence of side effects for placebo.

Take care to avoid operating a vehicle or other heavy machinery until you know how you react to Celexa. Celexa side effects may include impaired thinking and motor skills, or blurred vision.

Cautions: Celexa should be used cautiously in patients with: manic or bipolar disorders, blood circulation and metabolism difficulties, or a history of seizures. Celexa may not be an appropriate medication for patients with brain damage or disease, or congenital brain defects. Celexa dosages should be lower for patients with kidney or liver trouble. Tell your doctor if you have ever had an allergic reaction to Celexa, to an antidepressant or anxiety medication of any type, or any other medication.

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Celexa Interactions

Celexa and alcohol have not been shown to interfere with each other, but taking them together is not recommended. It is possible that the combination may be hard on the liver.

Certain medications and supplements may increase the risk of serotonin syndrome in combination with Celexa. Serotonin syndrome may cause confusion, restlessness, lowered coordination, shivering or trembling, diarrhea, fever, sweating, twitching, or behaving with an excitement you can not control. If you experience a cluster of these symptoms, and you suspect that it may be due to a drug interaction or overdose, seek medical attention immediately (this condition is very rare).

Celexa interactions with the following drugs may be limited by following your doctor's advice. Always tell your doctor if you are taking any of the following:

  • Anticonvulsants such as fosphenytoin, phenytoin, carbidopa, levodopa, or carbamazepine may require patient monitoring when used with Celexa.
  • Appetite suppressants like phentermine, fenfluramine, or sibutramine may cause serious and dangerous side effects in combination, do not combine these therapies.
  • Azole antifungals such as fluconazole, ketoconazole, or itraconazole, may alter your heartbeat if used with Celexa.
  • Benzodiazepines such as lorazepam, diazepam, triazolam, temazepam, chlordiazepoxide, alprazolam, clorazepate, halazepam, estazolam, clonazepam should be used cautiously with Celexa.
  • Beta Blockers - Drugs like propranolol, metoprolol, atenolol, and others may build up in the body to toxic levels when combined with SSRIs. Your doctor may adjust dosages to compensate.
  • Buspirone - Do not combine.
  • Berapamil - Increases blood levels of Celexa and increases risk of serotonin syndrome.
  • Diltiazem - Increases the risk of serotonin syndrome.
  • Dextromethorphan - Avoid combining.
  • Warfarin - may cause bleeding problems when used with Celexa. Your doctor may prevent this by adjusting the dosage of one of these medications.
  • Trazodone - Risk of Celexa toxicity.
  • Venlafaxine - When used with Celexa, increases the chance of developing the rare, but serious, side effect known as serotonin syndrome.
  • Gingko - May act as an MAO inhibitor, do not combine.
  • Ginseng - May act as an MAO inhibitor, do not combine.
  • Indian Snakeroot - Do not combine.
  • Kava kava - Acts centrally in the nervous system, do not combine with Celexa.
  • Digoxin
  • Lithium - Combine with caution, dosage adjustments may be required.
  • Macrolide antibiotics such as Azithromycin, Clarithromycin, and Erythromycin, may increase Celexa levels in the blood.
  • Ma Huang - Do not combine.
  • MAO inhibitors - Celexa must never be mixed with MAO (monoamine oxidase) inhibitors, a class of antidepressants and antisenility drugs, such as selegiline, furazolidone, phenelzine, isocarboxazid, or tranylcypromine. Never use Celexa within 5-6 weeks of starting or stopping an MAO inhibitor. This drug interaction could cause severe heart problems or death. Patients over 65 should allow a longer wait period between using Celexa and an MAO, as these medications may stay in their system longer than in other patients.
  • Migraine medications of the triptan class such as naratriptan, sumatriptan, rizatriptan, or zolmitriptan can cause coordination difficulties when mixed with SSRIs.
  • Narcotic pain medication like Cialis, meperidine, buprenorphine, propoxyphene, morphine, nalbuphine, oxycodone, butorphanol, pentazocine and hydrocodone should be used cautiously with Celexa, as these medications also act on the central nervous system.
  • Quinidine
  • Delavirdine - May lead to Celexa toxicity, avoid this combination.
  • Sedatives like butalbital, phenobarbitol, seconal, or other barbiturates.
  • Selective serotonin reuptake inhibitors (SSRIs) of any other type, like paroxetine, fluoxetine, fluvoxamine, or sertraline should not be mixed together.
  • Sleep medication like zolpidem, zaleplon, or over the counter sleeping pills should be used with Celexa only as, and if, advised by your doctor.
  • St. John's Wort - May raise serotonin levels too high, do not combine with Celexa.
  • Street drugs such as LSD, Ecstasy (MDMA), or marijuana. These drugs also affect serotonin levels in the brain and may react strongly with an SSRI like Celexa. These interactions have not been studied in clinical tests and the side effects may prove very dangerous.
  • Cimetidine
  • Dofetilide - Your doctor may decrease your dose of this medication to prevent increased blood levels.
  • Tranquilizers such as haloperidol or chlorpromazine may cause oversedation.
  • Tricyclic antidepressants such as amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, and trimipramine, may increase the risk of side effects from Celexa. The use of Celexa with these medications can increase the risk of developing serotonin syndrome.
  • Tryptophan or 5-HTP - This supplement may increase the risk of serotonin syndrome when mixed with Celexa.
  • Tramadol - May increase the risk of seizure, avoid this combination.
  • Sildenafil citrate
  • Bupropion

Talk with your doctor if you are considering mixing an antidepressant and anxiety medication like Celexa with any other antidepressant, or any medication that may cause drowsiness. Anxiety medication can have increased, unexpected, or severe side effects when mixed with other medications that affect the central nervous system.

Celexa Dosages

Your Celexa dosage should be the least amount required to treat your symptoms. Celexa dosages usually begin at 20 mg/day. The dosage may be stepped up at a rate of 10 mg/week according to your doctor's advice. If you are planning to stop taking Celexa, ask your doctor about reducing your dose gradually. It is not usually recommended for patients to stop Celexa all at once.

People with kidney or liver trouble, the elderly, or those with weak constitutions should take no more than 40 mg/day.

Maximum Celexa dosage should not exceed 60 mg/day. Celexa overdose may cause coma, irritability, dizziness, drowsiness, racing heartbeat, facial flushing, nausea, sweating, tremor, or vomiting, and should be treated by a healthcare professional immediately.

Celexa Directions

Celexa is normally taken once a day, and can be taken with or without food, except grapefruit juice. You should avoid grapefruit juice while you are on Celexa, as it may lead to increased blood levels of the drug. If you miss a dose, do not take a double dose the following day.

Celexa should be stopped slowly, by gradually decreasing dosage as directed by your doctor. Suddenly stopping Celexa treatment can cause increased side effects.

Celexa should be stored away from heat and light.

Celexa and Pregnancy

Celexa has not adequately been studied in humans for safety during pregnancy. Celexa has been studied in animals, and shown to increase the death and deformity rate in unborn animals at doses higher than typically prescribed. Incidences of retarded growth were also reported. Animal studies are not always predictive of results in humans, but Celexa is not generally recommended for pregnant women.

Advise your doctor if you are pregnant, or are planning a pregnancy if you are considering taking Celexa. The manufacturer recommends that Celexa be taken during pregnancy only if the benefit justifies the possible risk to the fetus.

Similar precautions apply for breastfeeding, as Celexa may pass to the child. Discuss the risks and benefits of treatment with your doctor.

Celexa and Children

Celexa has not been studied for use in children.

Celexa and Seniors

Celexa has not been shown to have different side effects in the elderly than in the general population, but it appears to stay in the system longer. Patients 65 years or older should try a lower starting dose of Celexa, with 20 mg/day being the recommended starting amount, up to a maximum of 40 mg/day.

 

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This document is provided for information only. It is not a substitute for consultation with a physician, either to diagnose symptoms or prescribe treatment. Any dosages mentioned are general guidelines only, please follow the directions of your doctor exactly when taking Celexa. We have made every effort to ensure that this information is accurate, but only your doctor can say if Celexa, or a drug combination, is safe for you. It should not be construed to indicate that to order and use Celexa is safe, appropriate, or effective for you. Consult your healthcare professional before you order Celexa online.
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