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Fluoxetine (Prozac)

Fluoxetine General Information

Fluoxetine Side Effects

Order fluoxetine online. Fluoxetine is used to treat major depression, obsessive-compulsive disorder, bulimia, and sometimes other eating disorders.

Fluoxetine Interactions

Fluoxetine Dosages

Fluoxetine Directions

Fluoxetine and Pregnancy

Fluoxetine and Children

Fluoxetine and Seniors

Fluoxetine General Information

Fluoxetine is used to treat major depression, obsessive-compulsive disorder, bulimia, and sometimes other eating disorders. Fluoxetine is also used to treat premenstrual dysphoric disorder (PMDD). In low doses, fluoxetine may be used to treat fibromyalgia.

Fluoxetine belongs to a family of antidepressants called selective serotonin re-uptake inhibitors (SSRIs), which are thought to improve mood by increasing the availability of a chemical in the brain called serotonin. High serotonin levels tend to be associated with a feeling of well-being, while depressed individuals often have low serotonin levels.

For best results, use fluoxetine regularly and consult your doctor about possible drug interactions.

Fluoxetine 20 mg capsules, manufactured by Laboratorios Vir S.A., come in multiples of 60 capsules.

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Product Price Quantity
Fluoxetine 20 mg, 60 cap $109
Fluoxetine 20 mg, 120 cap $199

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Fluoxetine Side Effects

Avoid operating a vehicle or other heavy machinery until you know how you react to Fluoxetine. Fluoxetine side effects may include impaired thinking and motor skills, or cause blurred vision.

Common fluoxetine side effects: sweating, agitation, dry mouth, decreased appetite, somnolence, dizziness, insomnia, tremor, headache, diarrhea, or nervousness.

Less common fluoxetine side effects: changes in sense of taste or vision, chest pain, constipation, dizziness, dry mouth, unusual feeling of warmth, flushed or reddened skin, increased sensitivity to sunlight, stomach cramps or gas, hair loss, weight loss, weight gain, priapism, decrease in your sex drive, increase in appetite, painful menstruation, yawning.

Tell your doctor immediately if you experience restlessness, rash, itching, hives, fever, chills, difficulty breathing, swelling, muscle pain, or joint pain as a result of taking fluoxetine. You may be allergic to fluoxetine, and have to stop taking it. These symptoms typically reverse as fluoxetine leaves your body, but for some symptoms, an antihistamine or steroid may be administered to speed recovery.

Seek medical attention if you experience flu symptoms, unsteadiness, convulsions, increased thirst, headache, anxiety, breast swelling, red or purple spotting on your skin, exhaustion, weakness, or an inability to concentrate.

Serotonin Syndrome - This rare side effect is possible with medications which affect serotonin levels, usually antidepressants. Some medications which only mildly affect serotonin metabolism on their own, or interfere with the metabolism of an antidepressant, may also increase the risk of this syndrome in combination with a medication like fluoxetine. The symptoms include agitation, confusion, diarrhea, fever, lack of coordination, shaking, shivering, sweating, trembling , twitching, or uncontrollable excitement. If you experience several of these symptoms at the same time, seek medical attention at once. If you cannot be taken to a hospital or doctor immediately, call 911 for instructions and help.

Cautions: Fluoxetine should be used cautiously in patients with: Parkinson's disease or a history of seizures, as it may worsen these conditions. Fluoxetine may not be right for patients with brain damage or disease, or congenital brain defects; it does not treat these conditions. Fluoxetine dosages should be lower for patients with liver trouble, as it will take them longer to absorb and remove the drug from their bodies. Patients with kidney trouble seem to process fluoxetine nearly the same as people without kidney impairment. Diabetic patients may need to adjust the dosage of their medication as fluoxetine may affect their blood sugar level. Fluoxetine may cause weight loss, which may be undesirable for some patients. Tell your doctor if you have ever had an allergic reaction to fluoxetine, Zoloft, Paxil, or any other medication.

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Fluoxetine Interactions

Certain medications and supplements may increase the risk of serotonin syndrome in combination with fluoxetine. Serotonin syndrome may cause confusion, restlessness, lowered coordination, shivering or trembling, diarrhea, fever, sweating, twitching, or behaving with an excitement you can not control. If you experience a cluster of these symptoms, and you suspect that it may be due to a drug interaction or overdose, seek medical attention immediately. (This condition is very rare.)

Consult a doctor about mixing any medication. Be especially careful to obtain medical advice if you are considering fluoxetine treatment and currently take any of the following medications.

  • Alcohol - Avoid alcohol while taking fluoxetine
  • Appetite suppressants like phentermine or sibutramine.
  • Benzodiazepines such as lorazepam, diazepam, triazolam, temazepam, chlordiazepoxide, alprazolam, clorazepate, halazepam, estazolam, clonazepam - Fluoxetine may increase blood levels of certain of these drugs, and may cause them to stay in the body longer.
  • Beta Blockers - Drugs like propranolol, metoprolol, atenolol, and others may build up in the body to toxic levels when combined with SSRIs.
  • Buspirone
  • Clozapine
  • Dextromethorphan
  • Warfarin - may cause bleeding problems when used with fluoxetine. Your doctor may prevent this by adjusting the dosage of one of these medications.
  • Digitoxin
  • Trazodone
  • Phenytoin
  • Venlafaxine - When used with fluoxetine, increases the chance of developing serotonin syndrome. Do not use venlafaxine within 5 weeks of stopping fluoxetine treatment.
  • Haloperidol
  • Heart Medicine (digitalis glycosides) - Your doctor may adjust your dosage of either the heart medication or the fluoxetine, as they may interfere with each other's levels in the blood.
  • Astemizole - May alter your heartbeat if used with fluoxetine.
  • Lithium (Eskalith)
  • Moclobemide - This medication should not be mixed with fluoxetine, and you should allow 7 days following the use of moclobemide before starting fluoxetine. Allow 5 full weeks after stopping fluoxetine before beginning use of moclobemide. Serious side effects, including serotonin syndrome can develop.
  • MAO inhibitors - Fluoxetine must never be mixed with MAO (monoamine oxidase) inhibitors, a class of antidepressants and antisenility drugs, such as selegiline, furazolidone, phenelzine, isocarboxazid, or tranylcypromine. Never use fluoxetine within 2 weeks of stopping an MAO inhibitor, wait for 5 weeks after stopping fluoxetine to begin use of an MAO inhibitor. This drug interaction could prove fatal. Patients over 65 years of age should allow a longer wait period between using fluoxetine and an MAO, as fluoxetine may stay in their system longer than in other patients.
  • Migraine medications of the triptan class such as naratriptan, sumatriptan, rizatriptan, or zolmitriptan can cause coordination difficulties when mixed with SSRIs.
  • Pimozide
  • Bromocriptine should be mixed cautiously with fluoxetine.
  • Sedatives like butalbital, phenobarbitol, Seconal, or other barbiturates.
  • Selective serotonin reuptake inhibitors (SSRIs) of any other type, like citalopram, paroxetine, fluvoxamine, or sertraline.
  • Nefazodone
  • Sinemet (carbidopa, levodopa)
  • Sleep medication like zolpidem, zaleplon, or over the counter sleeping pills should be used with fluoxetine only as, and if, advised by your doctor.
  • Street drugs such as LSD, Ecstasy (MDMA), or marijuana. These drugs also affect serotonin levels in the brain and may react strongly with an SSRI like fluoxetine. Do not combine.
  • Pentazocine
  • Flecainide
  • Carbamazepine
  • Thioridazine - Severe fluoxetine interactions can occur with this medication. Fluoxetine should not be taken sooner than two weeks after thioridazine, and fluoxetine treatment should be stopped for five weeks before taking thioridazine. This drug reaction could be suddenly fatal. Individuals with liver problems or who are over 65 should allow a longer wait period between using fluoxetine and thioridazine, as fluoxetine may stay in their system longer than in other patients.
  • Tranquilizers such as haloperidol or chlorpromazine may cause oversedation.
  • Tricyclic antidepressants such as amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, and trimipramine, may increase the risk of side effects from fluoxetine. The use of fluoxetine with these medications can increase the risk of developing serotonin syndrome.
  • Tryptophan or 5-HTP - This supplement may increase the risk of serotonin syndrome when mixed with fluoxetine.
  • Tramadol
  • Bupropion - May increase the risk of serious side effects, such as seizure, from bupropion.
  • Vinblastine

Be particularly careful about mixing fluoxetine with any prescription antidepressant, antipsychotic, or antianxiety medication. Check with your doctor about mixing fluoxetine with any central nervous system depressant, even if it is an over the counter medication.

Fluoxetine Dosages

The following dosages are average prescription recommendations for fluoxetine. If you doctor has prescribed a different dosage, take that and follow the dosage instructions that come with your fluoxetine prescription. Doses below are for adults, doses for children must be determined on an individual basis by a doctor.

  • Depression or Obsessive-Compulsive Disorder - 20 mg once per day is the usual starting dose. Dosage will rarely exceed 80 mg per day. Once the condition is under control, your doctor may switch you to Fluoxetine Weekly, at a usual dose of a 90 mg capsule taken once a week.
  • Bulimia Nervosa - 60 mg once per day is the usual dose. Dosage will rarely exceed 80 mg.
  • Premenstrual Dysphoric Disorder - 20 mg once per day is the usual starting dose. Dosage will rarely exceed 80 mg per day.

If you have missed a dose, skip it and return to your regular dosing schedule. Do not take double doses of fluoxetine.

When switching to Fluoxetine Weekly from a daily dose, the manufacturer suggests waiting a week after stopping the daily dose to begin taking the Fluoxetine Weekly dose. Taking Fluoxetine Weekly within a week of ending a daily regimen can cause blood levels of fluoxetine to increase beyond the usual concentration.

Fluoxetine Directions

It may take up to four weeks for fluoxetine to clear up depression, and up to six months to ensure that the condition will not return. It may take five weeks before fluoxetine begins to be effective for obsessive-compulsive disorder. Fluoxetine may begin to positively affect the symptoms of bulimia nervosa within a week, but it may be up to four weeks before the condition goes away.

Store fluoxetine away from heat and light, but do not freeze it. Store in a dry location; avoid storing it in the bathroom, near sinks, or other areas where it may become damp. Do not use fluoxetine after the expiration date. Do not crush Fluoxetine Weekly tablets.

Keep fluoxetine away from children; both when storing it, and when discarding any unused medication.

Take fluoxetine with food if you find that it upsets your stomach.

Fluoxetine and Pregnancy

Fluoxetine has not been studied for safety in pregnant or nursing mothers. Consult your doctor if you plan to become pregnant or breastfeed during treatment.

Fluoxetine and Children

Fluoxetine has been studied in some children aged 7-18. Fluoxetine appeared to be helpful in treating obsessive compulsive disorder and depression among this age group, but there is an increase in certain side effects. Children seem more likely to experience restlessness, agitation, excitement, and difficulty sleeping when treated with fluoxetine. More study is indicated, but fluoxetine is sometimes prescribed to young people in limited doses.

Fluoxetine and Seniors

Studies have not indicated that fluoxetine causes different side effects or reactions in the elderly than in the general adult population; however, fluoxetine may stay in the body longer. Elderly patients may need a lower, or less frequent prescription dose.

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This document is provided for information only. It is not a substitute for consultation with a physician, either to diagnose symptoms or prescribe treatment. Any dosages mentioned are general guidelines only, please follow the directions of your doctor exactly when taking fluoxetine. We have made every effort to ensure that this information is accurate, but only your doctor can say if fluoxetine, or a drug combination, is safe for you. It should not be construed to indicate that to order and use fluoxetine is safe, appropriate, or effective for you. Consult your healthcare professional before you order fluoxetine online.
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