Fluoxetine is used to treat major depression, obsessive-compulsive disorder, bulimia, and sometimes other eating disorders. Fluoxetine is also used to treat premenstrual dysphoric disorder (PMDD). In low doses, fluoxetine may be used to treat fibromyalgia.
Fluoxetine belongs to a family of antidepressants called selective
serotonin re-uptake inhibitors (SSRIs), which are thought
to improve mood by increasing the availability of a chemical
in the brain called serotonin. High serotonin levels tend
to be associated with a feeling of well-being, while depressed
individuals often have low serotonin levels.
For best results,
use fluoxetine regularly and consult your doctor about possible drug
Fluoxetine 20 mg capsules, manufactured by Laboratorios Vir S.A., come in multiples of 60 capsules.
Order Fluoxetine online
Avoid operating a vehicle or other heavy machinery until you know how you react to Fluoxetine. Fluoxetine side effects
may include impaired thinking and motor skills, or cause blurred
Common fluoxetine side effects: sweating, agitation, dry mouth,
decreased appetite, somnolence, dizziness, insomnia,
tremor, headache, diarrhea, or nervousness.
Less common fluoxetine side effects: changes in sense of taste
or vision, chest pain, constipation, dizziness, dry mouth,
unusual feeling of warmth, flushed or reddened skin, increased
sensitivity to sunlight, stomach cramps or gas, hair loss,
weight loss, weight gain, priapism, decrease in your sex drive,
increase in appetite, painful menstruation, yawning.
Tell your doctor immediately if you experience restlessness,
rash, itching, hives, fever, chills, difficulty breathing,
swelling, muscle pain, or joint pain as a result of taking
fluoxetine. You may be allergic to fluoxetine, and have to stop taking
it. These symptoms typically reverse as fluoxetine leaves your
body, but for some symptoms, an antihistamine or steroid may
be administered to speed recovery.
Seek medical attention if you experience flu symptoms, unsteadiness,
convulsions, increased thirst, headache, anxiety, breast swelling,
red or purple spotting on your skin, exhaustion, weakness,
or an inability to concentrate.
Serotonin Syndrome - This rare side effect is possible with medications
which affect serotonin levels, usually antidepressants. Some
medications which only mildly affect serotonin metabolism
on their own, or interfere with the metabolism of an antidepressant,
may also increase the risk of this syndrome in combination
with a medication like fluoxetine. The symptoms include agitation,
confusion, diarrhea, fever, lack of coordination, shaking,
shivering, sweating, trembling , twitching, or uncontrollable
excitement. If you experience several of these symptoms at
the same time, seek medical attention at once. If you cannot
be taken to a hospital or doctor immediately, call 911 for
instructions and help.
Cautions: Fluoxetine should be used cautiously in patients with:
Parkinson's disease or a history of seizures, as it may worsen
these conditions. Fluoxetine may not be right for patients with
brain damage or disease, or congenital brain defects; it does
not treat these conditions. Fluoxetine dosages should be lower
for patients with liver trouble, as it will take them longer
to absorb and remove the drug from their bodies. Patients
with kidney trouble seem to process fluoxetine nearly the same
as people without kidney impairment. Diabetic patients may need to adjust the dosage of their medication as fluoxetine may affect their blood sugar level. Fluoxetine may cause weight loss, which may be undesirable for some patients. Tell your
doctor if you have ever had an allergic reaction to
Zoloft, Paxil, or any other medication.
Certain medications and supplements may increase the risk of serotonin
syndrome in combination with fluoxetine. Serotonin syndrome may
cause confusion, restlessness, lowered coordination, shivering
or trembling, diarrhea, fever, sweating, twitching, or behaving
with an excitement you can not control. If you experience a
cluster of these symptoms, and you suspect that it may be
due to a drug interaction or overdose, seek medical attention
immediately. (This condition is very rare.)
Consult a doctor about mixing any medication. Be
especially careful to obtain medical advice if you are considering
fluoxetine treatment and currently take any of the following medications.
- Alcohol - Avoid alcohol while taking fluoxetine
- Appetite suppressants like phentermine or sibutramine.
- Benzodiazepines such as lorazepam, diazepam,
triazolam, temazepam, chlordiazepoxide,
clorazepate, halazepam, estazolam, clonazepam
- Fluoxetine may increase blood levels of certain of these drugs,
and may cause them to stay in the body longer.
- Beta Blockers - Drugs like propranolol, metoprolol, atenolol,
and others may build up in the body to toxic levels when combined
- Warfarin - may cause bleeding problems when used
with fluoxetine. Your doctor may prevent this by adjusting the dosage
of one of these medications.
- When used with fluoxetine, increases the chance of developing serotonin
syndrome. Do not use venlafaxine within 5 weeks of stopping
- Heart Medicine (digitalis glycosides) - Your doctor may adjust
your dosage of either the heart medication or the fluoxetine, as they
may interfere with each other's levels in the blood.
- Astemizole - May alter your heartbeat if used with fluoxetine.
- Lithium (Eskalith)
- Moclobemide - This medication should not be mixed
with fluoxetine, and you should allow 7 days following the use
of moclobemide before starting fluoxetine. Allow 5 full weeks after stopping
fluoxetine before beginning use of moclobemide. Serious side effects,
including serotonin syndrome can develop.
- MAO inhibitors - Fluoxetine must never be mixed with MAO (monoamine
oxidase) inhibitors, a class of antidepressants and antisenility
drugs, such as selegiline, furazolidone, phenelzine, isocarboxazid, or tranylcypromine.
Never use fluoxetine within 2 weeks of stopping an MAO inhibitor,
wait for 5 weeks after stopping fluoxetine to begin use of an MAO
inhibitor. This drug interaction could prove fatal.
Patients over 65 years of age should allow a longer wait period between using fluoxetine and an MAO, as fluoxetine may stay in their system longer than in other patients.
- Migraine medications of the triptan class such as naratriptan, sumatriptan, rizatriptan, or zolmitriptan can cause coordination difficulties when mixed with SSRIs.
- Bromocriptine should be mixed
cautiously with fluoxetine.
- Sedatives like butalbital, phenobarbitol,
Seconal, or other barbiturates.
- Selective serotonin reuptake inhibitors (SSRIs) of any other
type, like citalopram,
paroxetine, fluvoxamine, or sertraline.
- Sinemet (carbidopa, levodopa)
- Sleep medication like zolpidem, zaleplon,
or over the counter sleeping pills should be used with fluoxetine
only as, and if, advised by your doctor.
- Street drugs such as LSD, Ecstasy (MDMA), or marijuana. These
drugs also affect serotonin levels in the brain and may react
strongly with an SSRI like fluoxetine. Do not combine.
- Thioridazine - Severe
fluoxetine interactions can occur
with this medication. Fluoxetine should not be taken sooner
than two weeks after thioridazine, and fluoxetine treatment
should be stopped for five weeks before taking thioridazine.
This drug reaction could be suddenly fatal. Individuals
with liver problems or who are over 65 should allow a longer
wait period between using fluoxetine and thioridazine, as
may stay in their system longer than in other patients.
- Tranquilizers such as haloperidol or chlorpromazine may cause oversedation.
- Tricyclic antidepressants such as amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, and trimipramine, may increase the risk of side effects from
fluoxetine. The use
of fluoxetine with these medications can increase
the risk of developing serotonin syndrome.
- Tryptophan or 5-HTP - This supplement may increase the risk of
serotonin syndrome when mixed with fluoxetine.
- May increase the risk of serious side effects, such as
seizure, from bupropion.
Be particularly careful about mixing fluoxetine with any prescription
antidepressant, antipsychotic, or antianxiety medication.
Check with your doctor about mixing fluoxetine with any central nervous system depressant, even if it is an over the counter medication.
The following dosages are average prescription recommendations
for fluoxetine. If you doctor has prescribed a different
take that and follow the dosage instructions that come
with your fluoxetine prescription. Doses below are for adults,
doses for children must be determined on an individual basis
by a doctor.
- Depression or Obsessive-Compulsive Disorder - 20 mg once per
day is the usual starting dose. Dosage will rarely exceed
80 mg per day. Once the condition is under control, your
doctor may switch you to Fluoxetine Weekly, at a usual dose
of a 90 mg capsule taken once a week.
- Bulimia Nervosa - 60 mg once per day is the usual dose. Dosage
will rarely exceed 80 mg.
- Premenstrual Dysphoric Disorder - 20 mg once per day
is the usual starting dose. Dosage will rarely exceed 80 mg
If you have missed a dose, skip it and return to your regular dosing schedule.
Do not take double doses of fluoxetine.
When switching to Fluoxetine Weekly from a daily dose, the manufacturer
suggests waiting a week after stopping the daily dose to begin
taking the Fluoxetine Weekly dose. Taking Fluoxetine Weekly within
a week of ending a daily regimen can cause blood levels of
fluoxetine to increase beyond the usual concentration.
It may take up to four weeks for fluoxetine to clear up depression,
and up to six months to ensure that the condition will not
return. It may take five weeks before fluoxetine begins to be
effective for obsessive-compulsive disorder. Fluoxetine may begin
to positively affect the symptoms of bulimia nervosa within
a week, but it may be up to four weeks before the condition
Store fluoxetine away from heat and light, but do not freeze it. Store
in a dry location; avoid storing it in the bathroom, near
sinks, or other areas where it may become damp. Do not use
after the expiration date. Do not crush Fluoxetine Weekly tablets.
Keep fluoxetine away from children; both when storing it, and when
discarding any unused medication.
Take fluoxetine with food if you find that it upsets your stomach.
Fluoxetine has not been studied for safety in pregnant or nursing mothers.
Consult your doctor if you plan to become pregnant or breastfeed
Fluoxetine has been studied in some children aged 7-18.
to be helpful in treating obsessive compulsive disorder and
depression among this age group, but there is an increase
in certain side effects. Children seem more likely to experience
restlessness, agitation, excitement, and difficulty sleeping
when treated with fluoxetine. More study is indicated, but
is sometimes prescribed to young people in limited doses.
Studies have not indicated that fluoxetine causes different side effects
or reactions in the elderly than in the general adult population;
however, fluoxetine may stay in the body longer. Elderly patients
may need a lower, or less frequent prescription dose.
This document is provided for information only. It is not
a substitute for consultation with a physician, either to
diagnose symptoms or prescribe treatment. Any dosages mentioned
are general guidelines only, please follow the directions
of your doctor exactly when taking fluoxetine.
We have made every effort to ensure that this information is accurate, but only your doctor can say if fluoxetine, or a drug combination, is safe for you. It should not be
construed to indicate that to order and use fluoxetine is
safe, appropriate, or effective for you. Consult your
healthcare professional before you order fluoxetine online.