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Zoloft (sertraline HCl)

Zoloft General information

Zoloft Side Effects

Order zoloft online. Zoloft is an SSRI (selective serotonin reuptake inhibitor), which is thought to work by increasing the amount of serotonin (a chemical involved in communication between nerve cells) available to the brain, back to a normal level.

Zoloft Interactions

Zoloft Dosages

Zoloft Directions

Zoloft and Pregnancy

Zoloft and Children

Zoloft and Seniors

Zoloft General Information

Zoloft is an SSRI (selective serotonin reuptake inhibitor), which is thought to work by increasing the amount of serotonin (a chemical involved in communication between nerve cells) available to the brain, back to a normal level. Zoloft has been shown to be effective in relieving several kinds of emotional disturbance that decrease the ability to function normally. This includes:

  • Panic attacks
  • Depression
  • Posttraumatic stress syndrome
  • Obsessive-compulsive disorder
  • Fibromyalgia (in low doses)
  • Severe PMS or Pre-menstrual Dysphoric Disorder (PMDD)

Zoloft 50 mg, brand name Besitran, is manufactured by Pfizer and comes in packs of 30 tablets.

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Product Price Quantity
Zoloft 50 mg, 30 tab $119
Zoloft 100 mg, 30 tab $199

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Zoloft Side Effects

Zoloft side effects are usually temporary and rarely cause a level of discomfort that causes patients to want to stop treatment. Consult your physician for advice on how to alleviate side effects that persist or bother you.

Zoloft side effects: sweating, agitation, dry mouth, decreased appetite, somnolence (drowsiness), dizziness, insomnia, tremor, constipation, indigestion, diarrhea, decreased libido, yawn, nervousness, sexual side effects, or weight loss.

Avoid operating a vehicle or other heavy machinery until you know how you react to Zoloft. Zoloft side effects may include impaired thinking and motor skills, or blurred vision.

Dependence: Zoloft has not been seen to cause dependence or withdrawal symptoms.

Cautions: Zoloft should be used cautiously in patients with: manic disorders, blood circulation and metabolism difficulties, or a history of seizures. Zoloft may not be right for patients with brain damage or disease, or congenital brain defects. Zoloft dosages should be lower for patients with kidney or liver trouble. Zolof has not been studied in patients with heart disease. Tell your doctor if you have ever had an allergic reaction to Zoloft, or any other medication.

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Zoloft Interactions

Certain medications and supplements may increase the risk of serotonin syndrome in combination with Zoloft. Serotonin syndrome may cause confusion, restlessness, lowered coordination, shivering or trembling, diarrhea, fever, sweating, twitching, or behaving with an excitement you can't control. If you experience a cluster of these symptoms, and you suspect that it may be due to a drug interaction or overdose, seek medical attention immediately.

Zoloft may not mix well with all other medications, either prescription or over the counter. Some medications should not be mixed at all, and with others your doctor may want to adjust your dose to decrease the risk of side effects. Consult with your doctor if you are already taking, or intend to take, any of the following:

  • Alcohol - While Zoloft and alcohol have not been shown to interfere with each other, but taking them together is not recommended.
  • Antabuse
  • Appetite suppressants like Phentermine/Adipex or Meridia (sibutramine)
  • Benzodiazepines such as lorazepam, diazepam, triazolam, temazepam, chlordiazepoxide, alprazolam, clorazepate, halazepam, estazolam, clonazepam should probably not be mixed with Zoloft.
  • Beta Blockers - Drugs like propranolol, metoprolol, atenolol, and others may build up in the body to toxic levels when combined with SSRIs.
  • Buspirone
  • Cough medicine (dextromethorphan) or any over the counter cold medication.
  • Coumadin (warfarin) - may cause bleeding problems when used with Zoloft. Your doctor may prevent this by adjusting the dosage of one of these medications.
  • Digitoxin
  • Trazodone
  • Phenytoin
  • Venlafaxine - When used with Zoloft, increases the chance of developing serotonin syndrome.
  • Aastemizole - May alter your heartbeat if used with Zoloft.
  • Eskalith
  • Moclobemide - This medication should not be mixed with Zoloft, and you should allow a week following the use of modobemide before starting Zoloft. Allow 2 full weeks after stopping Zoloft before beginning use of modobemide. Serious side effects, including serotonin syndrome can develop.
  • MAO inhibitors - Zoloft must never be mixed with MAO (monoamine oxidase) inhibitors, a class of antidepressants and antisenility drugs, such as selegiline, furazolidone, phenelzine, isocarboxazid, or tranylcypromine. Never use Zoloft within 2 weeks of starting or stopping an MAO inhibitor. Patients over 65 years of age should allow a longer wait period between using Zoloft and an MAO, as Zoloft may stay in their system longer than in other patients.
  • Migraine medications of the triptan class such as naratriptan, sumatriptan, rizatriptan, or zolmitriptan can cause coordination difficulties when mixed with SSRIs.
  • Narcotic/opioid analgesics like Cialis, meperidine, buprenorphine, propoxyphene, hydromorphone, morphine, nalbuphine, oxycodone, oxycodone with acetaminophen, butorphanol, pentazocine, or hydrocodone with acetaminophen), hydrocodone with ibuprofen.
  • Bromocriptine should be mixed cautiously with Zoloft.
  • Propafenone
  • Sedatives like butalbital, phenobarbitol, seconal, or other barbiturates.
  • Selective serotonin reuptake inhibitors (SSRIs) of any other type, like citalopram, fluoxetine, fluvoxamine, or paroxetine.
  • Nefazodone
  • Carbidopa, levodopa)
  • Sleep medication like zolpidem, zaleplon, or over the counter sleeping pills should be used with Zoloft only as, and if, advised by your doctor.
  • Street drugs such as LSD, Ecstasy (MDMA), or marijuana. These drugs also affect serotonin levels in the brain and may react strongly with an SSRI like Zoloft.
  • Cimetidine
  • Thioridazine - Severe Zoloft interactions can occur with this medication. Zoloft should not be taken within two weeks of thioridazine. Patients over 65 years of age should allow a longer wait period between using Zoloft and thioridazine, as Zolof may stay in their system longer than in other patients.
  • Tranquilizers such as haloperidol or chlorpromazine may cause oversedation.
  • Tricyclic antidepressants such as amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, and trimipramine, may increase the risk of side effects from Zoloft.
  • Tryptophan or 5-HTP - This supplement may increase the risk of serotonin syndrome when mixed with Zoloft.
  • Tramadol
  • Sildenafil - Increased risk of side effects.
  • Bupropion - May increase risk of serious side effects from bupropion.

Talk with your doctor if you are considering mixing an antidepressant like Zoloft with any other antidepressant, or any medication that may cause drowsiness. Antidepressant medication can have increased, unexpected, or severe side effects when mixed with other medications that affect the central nervous system.

Zoloft Dosages

The usual starting dose of Zoloft is 25-50 mg per day, up to a maximum of 200 mg per day. Since Zoloft stays in the body for 24 hours, doses should be taken at the same time every day. Do not take double doses of Zoloft, and ask your doctor what to do about missed doses. Dosage should be increased at minimum intervals of a week, and stopped slowly according to your doctor's advice. Zoloft should not be abruptly started or stopped.

Zoloft Directions

Zoloft is normally taken once a day, and can be taken with or without food. If you miss a dose, do not take a double dose the following day. Zoloft may take several weeks to improve your condition.

Zoloft should be stopped slowly, by gradually decreasing dosage as directed by your doctor. Suddenly stopping treatment can cause increased side effects.

Keep Zoloft away from children; both when storing it, and when discarding any unused medication.

Zoloft and Pregnancy

Zoloft has not been shown to cause damage to the fetus during pregnancy, but it has not been fully studied in humans and proven safe. Advise your doctor if you are pregnant, or are planning a pregnancy if you are considering taking Zoloft. The manufacturer recommends that Zoloft be taken during pregnancy only if the benefit justifies the possible risk to the fetus.

Trace amounts of Zoloft pass through breast milk, but have not been demonstrated to be harmful to nursing babies. The long term effects are unknown and caution is advised.

Zoloft and Children

Zoloft has not been studied for use in children under 6.

Zoloft has been prescribed as a treatment for obsessive compulsive disorders in children from 6-17 years of age. The starting dose of Zoloft for children 6-12 is usually 25 mg, up to 200 mg per day. The starting dose of Zoloft for children 13-17 is usually 50 mg, up to 200 mg per day.

Zoloft and Seniors

Zoloft has not been observed to have different effects in the elderly than in the general population, but it appears to stay in the system longer. Patients 65 years or older should try a lower starting dose of Zoloft, 12.5 mg per day is common.

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This document is provided for information only. It is not a substitute for consultation with a physician, either to diagnose symptoms or prescribe treatment. Any dosages mentioned are general guidelines only, please follow the directions of your doctor exactly when taking Zoloft. We have made every effort to ensure that this information is accurate, but only your doctor can say if Zoloft, or a drug combination, is safe for you. It should not be construed to indicate that to buy and use Zoloft is safe, appropriate, or effective for you. Consult your healthcare professional before you order Zoloft online.
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