Zyban is a
nicotine-free quit-smoking aid. Zyban contains
the same active ingredient as the antidepressant medication
Wellbutrin. It works by boosting the levels of several chemical
messengers in the brain. With more of these chemicals at work, you
experience a reduction in nicotine withdrawal symptoms and a
weakening of the urge to smoke. More than a third of the people who
take Zyban while participating in a support program are able to quit
smoking for at least 1 month. Zyban can also prove helpful when
people with conditions such as chronic bronchitis and emphysema
decide it is time to quit.
About 1 person in 1,000 suffers a seizure while taking Zyban. For
this reason, people with epilepsy and certain other disorders should
never take the drug. Do not share Zyban with friends. Only a doctor
can decide whether Zyban is safe for a particular individual.
Zyban, manufactured by
GlaxoSmithKline, contains 150 mg bupropion. Zyban comes in
multiples of 60 tablets.
Order Zyban online
effects cannot be anticipated. If any develop or change in intensity,
inform your doctor as soon as possible. Only your doctor can
determine if it is safe for you to continue taking Zyban.
The most common Zyban side effects are:
Dry mouth and sleeplessness.
generally mild and usually disappear after a few weeks. If you have
difficulty sleeping, avoid taking Zyban close to bedtime and ask
your doctor about reducing your dosage.
Zyban side effects may include:
Abdominal pain, abnormal dreams, anxiety, constipation, diarrhea,
disturbed concentration, dizziness, joint pain, increased cough,
itching, nasal inflammation, nausea, nervousness, rash, sore throat.
Zyban side effects may include:
Abnormal thinking, allergic reaction, bronchitis, changes in
taste, difficulty breathing, dry skin, fever, hives, hot flashes,
increased appetite or loss of appetite, increased blood pressure,
migraine, mouth ulcers, muscle pain, neck pain, nosebleed, ringing
in the ears, shakiness, sinus inflammation, sleepiness, throbbing
effects may include: Chest pain, feeling of unhappiness, thirst,
swelling of the face.
Zyban has been known to trigger convulsions, no one with a seizure
disorder should take the drug. Also avoid Zyban if you are taking
Wellbutrin or any other drug that contains bupropion, Zyban's active
ingredient. The more bupropion you take, the more likely you are to
have a seizure.
seizure-triggering potential is greater in people with an eating
disorder such as bulimia or anorexia, and in those undergoing abrupt
withdrawal from alcohol, sedatives, and tranquilizers such as
Librium and Valium. If you suffer from one of these problems, never
take Zyban. Avoid it, too, if you are taking a drug classified as an
MAO inhibitor, such as the antidepressants Nardil and Parnate. Allow
at least 14 days to pass between taking one of these drugs and
starting your Zyban therapy.
chance of a seizure from Zyban rises with the amount in your system,
never take more than one 150-mg tablet at a time, and limit your
total daily intake to 2 doses (300 mg).
A variety of
conditions can predispose you to seizures, including:
nervous system tumors
Cirrhosis of the liver
withdrawal from alcohol, tranquilizers, or sedatives
Addiction to narcotics or cocaine
- Use of
over-the-counter stimulants or diet pills
- Use of
- Use of
antidepressants, major tranquilizers, steroids, or theophylline
If any of
these apply to you, use Zyban with care. If you do have a seizure
while taking Zyban, stop taking the drug and never take it again.
or any other ingredient in Zyban has ever given you an allergic
reaction, the drug is not for you.
Zyban and call your doctor immediately if you have difficulty
breathing or swallowing; notice swelling in your face, lips, tongue,
or throat; develop swollen arms and legs; or break out with itchy
eruptions. These are warning signs of a potentially severe allergic
If you have
a liver or kidney condition, make sure the doctor is aware of it.
Your dosage may need to be reduced (If you have severe cirrhosis of
the liver, your dosage must be reduced). Also make certain
the doctor knows about any heart condition you may have.
interfere with your driving ability. Do not drive or operate
dangerous machinery until you are certain of the drug's effect on
If Zyban is
used with certain other drugs, the effects of either could be
increased, decreased, or altered. It is especially important to
check with your doctor before combining Zyban with the following:
Antidepressants such as Norpramin, Pamelor, Paxil, Prozac,
Tofranil, and Zoloft
blockers (heart and blood pressure medications) such as Inderal,
Lopressor, and Tenormin
Heart-stabilizing drugs such as Rythmol and Tambocor
Levodopa (Dopar, Larodopa, Sinemet)
tranquilizers such as Haldol, Risperdal and Thorazine
inhibitors such as the antidepressants Nardil and Parnate
Steroids such as prednisone and hydrocortisone
Theophylline (Theo-Dur, Theolair)
smoking, with or without Zyban treatment, could change the way your
body metabolizes certain drugs, for example, theophylline and
warfarin (Coumadin). Make sure your doctor knows all the
prescription and over-the-counter medicines you are taking.
starting Zyban dose is one 150-mg tablet in the morning for the
first 3 days. After that, take one 150-mg tablet in the morning and
another in the early evening. Keep doses at least 8 hours apart. The
maximum recommended dose is 300 milligrams daily.
Zyban for 7 to 12 weeks. Your doctor may recommend continuing
treatment for up to 6 months.
If having a
and liver disease,
your doctor may
reduce the frequency of your doses to avoid high blood levels of
Zyban. If you have severe cirrhosis of the liver, you should take no
more than 150 mg every other day.
Zyban comes as a tablet to take by mouth.
Treatment with Zyban begins while you are still smoking.
Zyban needs about a week to reach an effective level in your
body; so to improve your chance of success, you should not
attempt to quit until the second week of treatment. Set a
firm date for quitting. If you are still smoking after that
date, your odds of breaking the habit will be worse. You
should keep taking Zyban for 7 to 12 weeks.
You can use
nicotine patches along with Zyban. However, combining the two
treatments can raise your blood pressure, so it is important to tell
your doctor if you plan to use both. Do not smoke while using a
patch, because too much nicotine can cause serious side effects.
Participating in a counseling or support program will make success
more likely. Your doctor can recommend a local program for you.
tablets whole. Do not chew, divide, or crush them. Take them exactly
If you miss
do not take an
extra tablet to "catch up" for the missed dose. Skip the dose and
take your next tablet at the regularly scheduled time.
Zyban overdose is limited. However, any medication taken in excess
can have serious consequences. If you suspect an overdose, seek
medical attention immediately.
Zyban overdose may include: Blurred vision, confusion,
grogginess, jitteriness, light-headedness, nausea, seizure,
sluggishness, visual hallucinations.
Store Zyban away from direct light and heat.
Store in a dry location; avoid storing it in the bathroom, near
sinks, or other areas where it may become damp. Do not use Zyban after the expiration date. Keep
away from children; both when storing it, and when discarding any
not been tested in pregnant women. If you are pregnant or plan to
become pregnant, do your best to quit smoking with the aid of
counseling and support before turning to drug therapy. For the sake
of the baby, you should avoid smoking or taking nicotine in any
other form while pregnant.
in breast milk and could affect a nursing infant. Ask your doctor
whether it will be better to discontinue the medication or to stop
The safety and
efficacy of Zyban have not been established in children under 18.
No specific information is available.
This document is provided for information only. It is not a substitute
for consultation with a physician, either to diagnose symptoms
or prescribe treatment. Any dosages mentioned are general
guidelines only, please follow the directions of your doctor exactly when taking
Zyban. We have made
every effort to ensure that this information is accurate,
but only your doctor can say if Zyban, or a drug combination,
is safe for you. It should not be construed to indicate that
to order and use Zyban is safe, appropriate, or effective
for you. Consult your healthcare professional before you order Zyban online.